1.
Scientific reasoning is a dialogue between the possible and the actual, between proposal and disposal between what might be true, and what is in fact the case.
Peter Medawar
2.
For a scientist must indeed be freely imaginative and yet skeptical, creative and yet a critic. There is a sense in which he must be free, but another in which his thought must be very preceisely regimented; there is poetry in science, but also a lot of bookkeeping.
Peter Medawar
3.
The alternative to thinking in evolutionary terms is not to think at all.
Peter Medawar
4.
The USA is so enormous, and so numerous are its schools, colleges and religious seminaries, many devoted to special religious beliefs ranging from the unorthodox to the dotty, that we can hardly wonder at its yielding a more bounteous harvest of gobbledygook than the rest of the world put together.
Peter Medawar
5.
Scientists are people of very dissimilar temperaments doing different things in very different ways. Among scientists are collectors, classifiers and compulsive tidiers-up; many are detectives by temperament and many are explorers; some are artists and others artisans. There are poet-scientists and philosopher-scientists and even a few mystics.
Peter Medawar
6.
The purpose of scientific enquiry is not to compile an inventory of factual information, nor to build up a totalitarian world picture of natural Laws in which every event that is not compulsory is forbidden. We should think of it rather as a logically articulated structure of justifiable beliefs about nature.
Peter Medawar
7.
Is the Scientific Paper a Fraud?
Peter Medawar
8.
The bells which toll for mankind are - most of them, anyway - like the bells of Alpine cattle; they are attached to our own necks, and it must be our fault if they do not make a cheerful and harmonious sound.
Peter Medawar
9.
It can be said with complete confidence that any scientist of any age who wants to make important discoveries must study important problems. Dull or piffling problems yield dull or piffling answers. It is not enough that a problem should be "interesting".
Peter Medawar
10.
Today the world changes so quickly that in growing up we take leave not just of youth but of the world we were young in.
Peter Medawar
11.
Psychoanalytic theory is the most stupendous intellectual confidence trick of the twentieth century and a terminal product as well-something akin to a dinosaur or zeppelin in the history of ideas, a vast structure of radically unsound design and with no posterity.
Peter Medawar
12.
It goes with the passionate intensity and deep conviction of the truth of a religious belief, and of course of the importance of the superstitious observances that go with it, that we should want others to share it - and the only certain way to cause a religious belief to be held by everyone is to liquidate nonbelievers. The price in blood and tears that mankind generally has had to pay for the comfort and spiritual refreshment that religion has brought to a few has been too great to justify our entrusting moral accountancy to religious belief.
Peter Medawar
13.
I cannot give any scientist of any age better advice than this: the intensity of a conviction that a hypothesis is true has no bearing over whether it is true or not.
Peter Medawar
14.
It is a common failing-and one that I have myself suffered from-to fall in love with a hypothesis and to be unwilling to take no for an answer. A love affair with a pet hypothesis can waste years of precious time. There is very often no finally decisive yes, though quite often there can be a decisive no.
Peter Medawar
15.
Scientists are entitled to be proud of their accomplishments, and what accomplishments can they call 'theirs' except the things they have done or thought of first? People who criticize scientists for wanting to enjoy the satisfaction of intellectual ownership are confusing possessiveness with pride of possession. Meanness, secretiveness and, sharp practice are as much despised by scientists as by other decent people in the world of ordinary everyday affairs; nor, in my experience, is generosity less common among them, or less highly esteemed.
Peter Medawar
16.
Innocent, unbiased observation is a myth.
Peter Medawar
17.
I once spoke to a human geneticist who declared that the notion of intelligence was quite meaningless, so I tried calling him unintelligent. He was annoyed, and it did not appease him when I went on to ask how he came to attach such a clear meaning to the notion of lack of intelligence. We never spoke again.
Peter Medawar
18.
The human mind treats a new idea the same way the body treats a strange protein; it rejects it.
Peter Medawar
19.
The fact that scientists do not consciously practice a formal methodology is very poor evidence that no such methodology exists. It could be said-has been said-that there is a distinctive methodology of science which scientists practice unwittingly, like the chap in Moliere who found that all his life, unknowingly, he had been speaking prose.
Peter Medawar
20.
[A certain class of explanations in science are] analgesics that dull the ache of incomprehension without removing the cause.
Peter Medawar
21.
If a scientist were to cut his ear off, no one would take it as evidence of a heightened sensibility.
Peter Medawar
22.
The art of research [is] the art of making difficult problems soluble by devising means of getting at them.
Peter Medawar
23.
When asked to make the formal declaration that I did not intend to overthrow the Constitution of the United States, I was fool enough to reply that I had no such purpose, but that were I to do it by mistake I should be inexpressibly contrite.
Peter Medawar
24.
If politics is the art of the possible, research is surely the art of the soluble. Both are immensely practical-minded affairs.
Peter Medawar
25.
Heredity proposes and development disposes.
Peter Medawar
26.
The attempt to discover and promulgate the truth is nevertheless an obligation upon all scientists, one that must be persevered in no matter what the rebuffs—for otherwise what is the point in being a scientist?
Peter Medawar
27.
Considered in its entirety, psychoanalysis won't do. It is an end product, moreover, like a dinosaur or a zeppelin; no better theory can ever be erected on its ruins, which will remain for ever one of the saddest and strangest of all landmarks in the history of twentieth century thought.
Peter Medawar
28.
How have people come to be taken in by The Phenomenon of Man? We must not underestimate the size of the market for works of this kind [pseudoscience/'woo'], for philosophy-fiction. Just as compulsory primary education created a market catered for by cheap dailies and weeklies, so the spread of secondary and latterly tertiary education has created a large population of people, often with well-developed literary and scholarly tastes, who have been educated far beyond their capacity to undertake analytical thought.
Peter Medawar
29.
Freudian psychoanalytical theory is a mythology that answers pretty well to Levi-Strauss's descriptions. It brings some kind of order into incoherence; it, too, hangs together, makes sense, leaves no loose ends, and is never (but never) at a loss for explanation. In a state of bewilderment it may therefore bring comfort and relief.... give its subject a new and deeper understanding of his own condition and of the nature of his relationship to his fellow men. A mythical structure will be built up around him which makes sense and is believable-in, regardless of whether or not it is true.
Peter Medawar
30.
To abdicate from the rule of reason and substitute for it an authentication of belief by the intentness and degree of conviction with which we hold it can be perilous and destructive. Religious beliefs give a spurious spiritual dimension to tribal enmities.
Peter Medawar
31.
You have ... been told that science grows like an organism. You have been told that, if we today see further than our predecessors, it is only because we stand on their shoulders. But this [Nobel Prize Presentation] is an occasion on which I should prefer to remember, not the giants upon whose shoulders we stood, but the friends with whom we stood arm in arm ... colleagues in so much of my work.
Peter Medawar
32.
Simultaneous discovery is utterly commonplace, and it was only the rarity of scientists, not the inherent improbability of the phenomenon, that made it remarkable in the past. Scientists on the same road may be expected to arrive at the same destination, often not far apart.
Peter Medawar
33.
The Phenomenon of Man stands square in the tradition of Naturphilosophie, a philosophical indoor pastime of German origin which does not seem even by accident (though there is a great deal of it) to have contributed anything of permanent value to the storehouse of human thought.
Peter Medawar
34.
A scientist is no more a collector and classifier of facts than a historian is a man who complies and classifies a chronology of the dates of great battles and major discoveries.
Peter Medawar
35.
If the task of scientific methodology is to piece together an account of what scientists actually do, then the testimony of biologists should be heard with specially close attention. Biologists work very close to the frontier between bewilderment and understanding.
Biology is complex, messy and richly various, like real life; it travels faster nowadays than physics or chemistry (which is just as well, since it has so much farther to go), and it travels nearer to the ground. It should therefore give us a specially direct and immediate insight into science in the making.
Peter Medawar
36.
No scientist is admired for failing in the attempt to solve problems that lie beyond his competence. ... Good scientists study the most important problems they think they can solve. It is, after all, their professional business to solve problems, not merely to grapple with them.
Peter Medawar
37.
A danger sign that fellow-obsessionals will at once recognize is the tendency to regard the happiest moments of your life as those that occur when someone who has an appointment to see you is prevented from coming.
Peter Medawar
38.
It is ... a sign of the times-though our brothers of physics and chemistry may smile to hear me say so-that biology is now a science in which theories can be devised: theories which lead to predictions and predictions which sometimes turn out to be correct. These facts confirm me in a belief I hold most passionately-that biology is the heir of all the sciences.
Peter Medawar
39.
It is not envy or malice, as so many people think, but utter despair that has persuaded many educational reformers to recommend the abolition of the English public schools.
Peter Medawar
40.
We shall not read it for its sociological insights, which are non-existent, nor as science fiction, because it has a general air of implausibility; but there is one high poetic fancy in the New Atlantis that stays in the mind after all its fancies and inventions have been forgotten. In the New Atlantis, an island kingdom lying in very distant seas, the only commodity of external trade is light: Bacon's own special light, the light of understanding.
Peter Medawar
41.
Deductivism in mathematical literature and inductivism in scientific papers are simply the postures we choose to be seen in when the curtain goes up and the public sees us. The theatrical illusion is shattered if we ask what goes on behind the scenes. In real life discovery and justification are almost always different processes.
Peter Medawar
42.
I do not believe indeed, I deem it a comic blunder to believe that the exercise of reason is sufficient to explain our condition and where necessary to remedy it, but I do believe that the exercise of reason is at all times necessary.
Peter Medawar
43.
Ask a scientist what he conceives the scientific method to be and he will adopt an expression that is at once solemn and shifty-eyed: solemn, because he feels he ought to declare an opinion; shifty-eyed, because he is wondering how to conceal the fact that he has no opinion to declare.
Peter Medawar
44.
We cannot point to a single definitive solution of any one of the problems that confront us — political, economic, social or moral, that is, having to do with the conduct of life. We are still beginners, and for that reason may hope to improve. To deride the hope of progress is the ultimate fatuity, the last word in poverty of spirit and meanness of mind. There is no need to be dismayed by the fact that we cannot yet envisage a definitive solution of our problems, a resting-place beyond which we need not try to go.
Peter Medawar
45.
French is not a language that lends itself naturally to the opaque and ponderous idiom of nature-philosophy, and Teilhard has according resorted to the use of that tipsy, euphoristic prose-poetry which is one of the more tiresome manifestations of the French spirit.
Peter Medawar
46.
I regret my disbelief in God.
Peter Medawar
47.
It is high time that laymen abandoned the misleading belief that scientific enquiry is a cold dispassionate enterprise, bleached of imaginative qualities, and that a scientist is a man who turns the handle of discovery; for at every level of endeavour scientific research is a passionate undertaking and the Promotion of Natural Knowledge depends above all on a sortee into what can be imagined but is not yet known.
Peter Medawar
48.
In no sense other than an utterly trivial one is reproduction the inverse of chemical disintegration. It is a misunderstanding of genetics to suppose that reproduction is only 'intended' to make facsimiles, for parasexual processes of genetical exchange are to be found in the simplest living things.
Peter Medawar
49.
I reckon that for all the use it has been to science about four-fifths of my time has been wasted, and I believe this to be the common lot of people who are not merely playing follow-my-leader in research.
Peter Medawar
50.
The intensity of a conviction that a hypothesis is true has no bearing on whether it is true or false. The importance of the strength of our conviction is only to provide a proportionately strong incentive to find out if the hypothesis will stand up to critical evaluation.
Peter Medawar